While Mcleish takes care of his niece and nephew, the puppies try to place a sweet but scary dog.
A trio of Marx brothers-esque dogs called the Three Wise Guys arrive at the Pound in search of the Star Pup, a dog destined to defeat Captain Slaughter. The Star Pup is easily identified by a star-shaped birthmark. But when Nose Marie is suddenly idenified as the Star Pup by the mark on her neck, she is celebrated. But does she have the knowhow to beat the captain?
The puppies sneak into a museum to place a pup with the curator's granddaughter; Niblet and Squirt face a cat mummy.
McLeish finds Strudel's super-hearing electronic Hearmuffs and starts hearing strange things that lead him to believe the dogs are aliens.
Noodles feels left out when his humans bring home a baby named J.D., and comes up with a crazy plan to get rid of him.
During an island adventure, Solo, an adventurous pup, wanders off into the jungle and it's up to the Pound Puppies to save him before a volcano erupts.