Andy Garcia, Real Housewives of OC, Justin Bieber
Sandra Bullock, Derek Luke, Shakira
Laurence Fishburne , Olivia Munn, Los Lobos
Taye Diggs, Kaley Kuoko, Ruben Paul
Laurence Fishburne , Olivia Munn, Los Lobos
Cedric the Entertainer, Corona Girl & Morrissey
Cedric the Entertainer, Corona Girl & Morrissey
After George's opening standup, which was G-rated due to all the kids in the crowd, "Creepy Little Sitcom Mom" (Belita Moreno) paid a visit to deliver bad news about George's old haircuts, among other things. Belita then joined George on the stage to reminisce about their work together on the show. She also admitted to stealing a few mementos from the set. Constance Marie joined them and talked about the early days of the sitcom, when George was a novice actor... and how George's real-life wife cast her as George's sitcom wife! Then, Valente Rodriguez joined the party -- the guy who can make George laugh like no one else can. George welcomed the kids from the show -- Luis Armand Garcia, Masiela Lusha and Aimee Garcia. They thanked George for the experience of working on "George Lopez" and talked about how their lives have changed since then. George got teary-eyed as he shared his thoughts on what the show means to him. Then came the "George Lopez" finale they never got to make, which included a cameo by Leah Remini.
Mark Harmon, 50 Cent
Ray Romano, Lake Bell & "Jersey Shore"
David Beckham & Mariah Carey
Ray Romano, Lake Bell & "Jersey Shore"
Larry David, Lisa Lampanelli, Jay Sean, Birdman
Samuel L, Jackson, Dianna Agron
Cheech and Chong, Regina King
Amber Valletta, Mark Valley
Brendan Fraser, Khloe and Kourtney Kardashian
Tyrese Gibson, Betty White
Samuel L, Jackson, Dianna Agron
Cheech and Chong, Regina King
Sofía Vergara, James Van Der Beek
Chris Jericho, David Arquette, Elizabeth Chavira,Trey Songz
Eric Andre, Eva Longoria, Sinbad
John Corbett, Mark Littell, Nicole Scherzinger, Steve Lyons
Brandy, Ray J
Bruno Tonioli, George Wallace, Taraji P. Henson
Slash, Zachary Levi
Chris Rock, Oscar De La Hoya, Sugar Shane Mosley
Luke Wilson, Monica
Kara Dioguardi, Cheech Marin & Tommy Chong, Jason Reeves
Angela Kinsey, Brendan Fraser, Jason Aldean
Chris Evans, Idris Elba, Lowell Sanders, Zoe Saldana
Jennifer Lopez, Ken Jeong, Ozomatli
Lopez Tonight celebrates its 100th episode, with guests Kobe Bryant and Louis C.K. with special appearances from Arsenio Hall, Clint Eastwood, Tom Cruise, Donald Trump, Russell Brand, and Eddie Van Halen. At the end of the show, George alongside his band performed the Van Halen song "Panama".