James Lipton interviews the actor, who reveals the impact of the death of his Brokeback Mountain co-star and friend Heath Ledger in 2008. Gyllenhaal chats about his recent role in Denis Villeneuve's Prisoners, his film debut as Billy Crystal's son in City Slickers and his big break in cult classic Donnie Darko. He also reminisces about working with Anne Hathaway on Love & Other Drugs and talks about his relationship with his actress sister Maggie
