Assasins depicts nine misfit men and women who attempted (four of them successfully) to assassinate American Presidents. While every nation has its assassins and would-be assassins, only in America, the authors suggest, do disturbed and disturbing individuals act not because they hope to influence national politics, but because they are wrapped up in a malignant sense of entitlement. Feeling betrayed by the failed promise of American democracy and the American Dream, they strike out at the symbol for America: the American President. Assassins spans several musical styles and many decades in a dizzying series of musical and theatrical inventions that culminate in the assassination of John F. Kennedy.